About: Abiraterone Acetate     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Abiraterone Acetate
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
  • Steroid
Preferred_Name
  • Abiraterone Acetate
UMLS_CUI
  • C0289343
CAS_Registry
  • 154229-18-2
Accepted_Therapeutic_Use_For
  • Castration-resistant prostate cancer
FDA_UNII_Code
  • EM5OCB9YJ6
Contributing_Source
  • FDA
ALT_DEFINITION
  • A substance being studied in the treatment of prostate cancer and breast cancer. It blocks tissues from making androgens (male hormones), such as testosterone. This may cause the death of cancer cells that need androgens to grow. It is a type of anti-androgen.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 552704
PDQ_Closed_Trial_Search_ID
  • 552704
Chemical_Formula
  • C26H33NO2
Legacy_Concept_Name
  • Abiraterone_Acetate
FULL_SYN
  • 17-(3-Pyridyl)-5,16-androstadien-3beta-acetateSNNCI
  • abiraterone acetatePTNCI-GLOSSCDR0000641969
  • CB7630CNNCI
  • ZytigaBRNCI
  • Androsta-5,16-dien-3-ol, 17-(3-pyridinyl)-, acetate (ester), (3beta)-SNNCI
  • Abiraterone AcetatePTNCI
  • ABIRATERONE ACETATEPTFDAEM5OCB9YJ6
DEFINITION
  • An orally active acetate salt of the steroidal compound abiraterone with antiandrogen activity. Abiraterone inhibits the enzymatic activity of steroid 17alpha-monooxygenase (17alpha-hydrolase/C17,20 lyase complex), a member of the cytochrome p450 family that catalyzes the 17alpha-hydroxylation of steroid intermediates involved in testosterone synthesis. Administration of this agent may suppress testosterone production by both the testes and the adrenals to castrate-range levels.NCI
code
  • C68845
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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