About: LSP1 wt Allele     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • LSP1 wt Allele
rdfs:subClassOf
OMIM_Number
  • 153432
GenBank_Accession_Number
  • NM_002339
Semantic_Type
  • Gene or Genome
Preferred_Name
  • LSP1 wt Allele
PubMedID_Primary_Reference
  • 17529967
UMLS_CUI
  • C2346628
EntrezGene_ID
  • 4046
Legacy_Concept_Name
  • LSP1_wt_Allele
HGNC_ID
  • HGNC:6707
FULL_SYN
  • LSP1 wt AllelePTNCI
  • WP34SYNCI
  • pp52SYNCI
  • Lymphocyte-Specific Protein 1 wt AlleleSYNCI
DEFINITION
  • Human LSP1 wild-type allele is located in the vicinity of 11p15.5 and is approximately 39 kb in length. This allele, which encodes lymphocyte-specific protein 1, may be involved in the regulation of neutrophil motility, adhesion, and transendothelial migration.NCI
DesignNote
  • The LSP1 genes can undergo alternative splicing, which results in multiple transcript variants encoding different isoforms. A SNP has been identified in the LSP1 gene (rs3817198), which is associated with increases in breast cancer incidence. (Nature 2007; 447:1087-1093)
code
  • C68714
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