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AttributesValues
rdf:type
rdfs:label
  • Daniquidone
rdfs:subClassOf
Has_Target
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Daniquidone
NSC_Code
  • 320846
UMLS_CUI
  • C0053006
CAS_Registry
  • 67199-66-0
FDA_UNII_Code
  • E780TX33D2
Contributing_Source
  • FDA
ALT_DEFINITION
  • A substance being studied in the treatment of cancer. It may kill cancer cells by causing damage to the DNA. Batracylin is a type of heterocyclic aryl amine.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 539029
PDQ_Closed_Trial_Search_ID
  • 539029
Chemical_Formula
  • C15H11N3O
Legacy_Concept_Name
  • Daniquidone
FULL_SYN
  • DaniquidonePTNCI
  • batracylinPTNCI-GLOSSCDR0000543117
  • 8-Aminoisoindolo(1,2-b)quinazolin-12(10H)-oneSNNCI
  • DANIQUIDONEPTFDAE780TX33D2
  • Bay H 2049CNNCI
  • BatracylinSYNCI
DEFINITION
  • A water-insoluble heterocyclic amide with potential antineoplastic activity. Daniquidone inhibits topoisomerases I and II, thereby inhibiting DNA replication and repair, and RNA and protein synthesis. The acetylated form of daniquidone is highly toxic and is capable of inducing unscheduled DNA synthesis; rapid acetylators are more likely to experience toxicity with this agent.NCI
code
  • C66984
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