About: Omeprazole Magnesium     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Omeprazole Magnesium
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Omeprazole Magnesium
UMLS_CUI
  • C0771765
CAS_Registry
  • 95382-33-5
FDA_UNII_Code
  • 426QFE7XLK
Contributing_Source
  • FDA
Chemical_Formula
  • 2C17H18N3O3S.Mg
Legacy_Concept_Name
  • Omeprazole_Magnesium
FULL_SYN
  • OMEPRAZOLE MAGNESIUMPTFDA426QFE7XLK
  • Omeprazole MagnesiumPTNCI
DEFINITION
  • The magnesium salt form of a benzimidazole with selective and irreversible proton pump inhibitor activity. In the acidic compartment of parietal cells, omeprazole is protonated and converted into the active achiral sulfenamide; the active sulfenamide forms one or more covalent disulfide bonds with the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase), thereby inhibiting its activity and the parietal cell secretion of H+ ions into the gastric lumen, the final step in gastric acid production. H+/K+ ATPase is an integral membrane protein of the gastric parietal cell.NCI
code
  • C66256
sameAs
is Has_Salt_Form of
is sameAs of
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