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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Liranaftate
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Liranaftate
UMLS_CUI
  • C1173390
CAS_Registry
  • 88678-31-3
FDA_UNII_Code
  • 5253IGO5X3
Contributing_Source
  • FDA
Chemical_Formula
  • C18H20N2O2S
Legacy_Concept_Name
  • Liranaftate
FULL_SYN
  • LiranaftatePTNCI
  • M-732CNNCI
  • (6-Methoxy-2-pyridinyl)methylcarbamothioic acid O-(5,6,7,8-tetrahydro-2-naphthalenyl) esterSNNCI
  • ZefnartFBNCI
  • LIRANAFTATEPTFDA5253IGO5X3
DEFINITION
  • A thiocarbamate and squalene epoxidase inhibitor with antifungal activity. Liranaftate inhibits fungal squalene epoxidase, an enzyme that plays a key role in the synthesis of sterol which is essential for cell membrane integrity. By preventing ergosterol synthesis and causing accumulation of squalene, this agent increases cell membrane permeability, cell leakage and eventually cell lysis.NCI
code
  • C66019
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