About: Hydroxystilbamidine     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Hydroxystilbamidine
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Hydroxystilbamidine
UMLS_CUI
  • C0063195
CAS_Registry
  • 495-99-8
FDA_UNII_Code
  • 39J262E49W
Contributing_Source
  • FDA
Chemical_Formula
  • C16H16N4O
Legacy_Concept_Name
  • Hydroxystilbamidine
FULL_SYN
  • HydroxystilbamidinePTNCI
  • HYDROXYSTILBAMIDINEPTFDA39J262E49W
DEFINITION
  • A cationic dye with antifungal, antitrypanosomal, antimalarial, and carcinostatic activities. Hydroxystilbamidine is able to bind to DNA and RNA in a non-intercalating manner, and is a powerful inhibitor of ribonucleases, thereby impeding cellular processes in protozoa. This agent was also shown to bind to and stablize trypanosomal lysosomes. Hydroxystilbamidine is commonly used as a diagnostic agent in neuroanatomy and as a histochemical stain.NCI
code
  • C65870
http://linked.open...y/mesh/hasConcept
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