About: Formoterol     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Formoterol
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Formoterol
UMLS_CUI
  • C0060657
CAS_Registry
  • 73573-87-2
FDA_UNII_Code
  • 5ZZ84GCW8B
Contributing_Source
  • FDA
Chemical_Formula
  • C19H24N2O4
Legacy_Concept_Name
  • Formoterol
CHEBI_ID
  • CHEBI:5147
FULL_SYN
  • EformoterolSYNCI
  • FORMOTEROLPTFDA5ZZ84GCW8B
  • FormoterolPTNCI
DEFINITION
  • A long-acting beta-adrenergic receptor agonist with bronchodilator activity. Formoterol selectively binds to beta-2 adrenergic receptors in bronchial smooth muscle, thereby activating intracellular adenyl cyclase, an enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3',5'-adenosine monophosphate (cAMP). Increased cAMP levels cause relaxation of bronchial smooth muscle, relieve bronchospasms, improve mucociliary clearance and reduce mediator substance release from inflammatory cells, especially from mast cells.NCI
code
  • C65754
sameAs
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