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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Misonidazole
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Misonidazole
NSC_Code
  • 261037
UMLS_CUI
  • C0026218
CAS_Registry
  • 13551-87-6
FDA_UNII_Code
  • 8FE7LTN8XE
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 39504
PDQ_Closed_Trial_Search_ID
  • 39504
Chemical_Formula
  • C7H11N3O4
Legacy_Concept_Name
  • Misonidazole
FULL_SYN
  • MISONIDAZOLEPTFDA8FE7LTN8XE
  • MisonidazolePTNCI
  • RO 7-0582SYDTPNSC0261037
  • 1-(alpha-methoxymethyl ethanol)-2-NitroimidazoleSNNCI
  • Ro-7-0582CNNCI
  • Ro-07-0582CNNCI
DEFINITION
  • A nitroimidazole with radiosensitizing and antineoplastic properties. Exhibiting high electron affinity, misonidazole induces the formation of free radicals and depletes radioprotective thiols, thereby sensitizing hypoxic cells to the cytotoxic effects of ionizing radiation. This single-strand breaks in DNA induced by this agent result in the inhibition of DNA synthesis. (NCI04)NCI
code
  • C657
sameAs
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