About: Ciclopirox Olamine     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Ciclopirox Olamine
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Ciclopirox Olamine
UMLS_CUI
  • C0126169
CAS_Registry
  • 41621-49-2
FDA_UNII_Code
  • 50MD4SB4AP
Contributing_Source
  • FDA
Chemical_Formula
  • C12H17NO2.C2H7NO
Legacy_Concept_Name
  • Ciclopirox_Olamine
CHEBI_ID
  • CHEBI:31398
FULL_SYN
  • Ciclopirox OlaminePTNCI
  • CICLOPIROX OLAMINEPTFDA50MD4SB4AP
DEFINITION
  • The olamine salt form of ciclopirox, a synthetic, broad-spectrum antifungal agent with additional antibacterial and anti-inflammatory activities. Ciclopirox exerts its action by binding to and chelating trivalent cations, such as Fe3+ and Al3+, thereby inhibiting the availability of essential co-factors for enzymes. This may lead to a loss of activity of enzymes that are essential for cellular metabolism, organization of cell wall structure and other crucial cell functions. In addition, ciclopirox exerts its anti-inflammatory activity by inhibiting 5-lipoxygenase and cyclooxygenase (COX).NCI
code
  • C65327
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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