About: Vancomycin Hydrochloride     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Vancomycin Hydrochloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Vancomycin Hydrochloride
UMLS_CUI
  • C0205992
CAS_Registry
  • 1404-93-9
FDA_UNII_Code
  • 71WO621TJD
Contributing_Source
  • FDA
Chemical_Formula
  • C66H75Cl2N9O24.ClH
Legacy_Concept_Name
  • Vancomycin_Hydrochloride
FULL_SYN
  • Vancomycin HydrochloridePTNCI
  • VANCOMYCIN HYDROCHLORIDEPTFDA71WO621TJD
DEFINITION
  • The hydrochloride salt of vancomycin, a branched tricyclic glycosylated peptide with bactericidal activity against most organisms and bacteriostatic effect on enterococci. At a site different from that of penicillins and cephalosporins, vancomycin binds tightly to the D-alanyl-D-alanine portion of cell wall precursors, thereby interfering with bacterial cell wall synthesis. This leads to activation of bacterial autolysins that destroy the cell wall by lysis. Vancomycin may also alter the permeability of bacterial cytoplasmic membranes and may selectively inhibit RNA synthesis.NCI
code
  • C65207
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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