About: Metronidazole     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Metronidazole
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Metronidazole
NSC_Code
  • 50364
  • 69587
UMLS_CUI
  • C0025872
CAS_Registry
  • 443-48-1
FDA_UNII_Code
  • 140QMO216E
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug that is used to treat infection and is being studied in the treatment of cancer. It is a type of antibacterial, antiprotozoal, and anthelmintic.NCI-GLOSS
Chemical_Formula
  • C6H9N3O3
Legacy_Concept_Name
  • Metronidazole
CHEBI_ID
  • CHEBI:6909
FULL_SYN
  • METRONIDAZOLEPTFDA140QMO216E
  • MetronidazolePTNCI
  • FlagylSYDTPNSC0069587
  • TricomSYDTPNSC0069587
  • Flagyl I.V. RTUBRNCI
  • FlagylPTNCI-GLOSSCDR0000413945
  • metronidazolePTNCI-GLOSSCDR0000045226
DEFINITION
  • A synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities. Although its mechanism of action is not fully elucidated, un-ionized metronidazole is readily taken up by obligate anaerobic organisms and is subsequently reduced by low-redox potential electron-transport proteins to an active, intermediate product. Reduced metronidazole causes DNA strand breaks, thereby inhibiting DNA synthesis and bacterial cell growth.NCI
code
  • C651
sameAs
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