About: Medroxyprogesterone     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Medroxyprogesterone
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
  • Steroid
Preferred_Name
  • Medroxyprogesterone
NSC_Code
  • 27408
UMLS_CUI
  • C0025147
CAS_Registry
  • 520-85-4
Accepted_Therapeutic_Use_For
  • Breast carcinoma; Contraception; Endometrial carcinoma; Renal cell carcinoma
In_Clinical_Trial_For
  • Alzheimer disease; Breast cancer; Endometrial cancer
FDA_UNII_Code
  • HSU1C9YRES
Contributing_Source
  • FDA
ALT_DEFINITION
  • A hormonal anticancer drug that is also used in cancer prevention. It belongs to the family of drugs called progestins.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 39813
PDQ_Closed_Trial_Search_ID
  • 39813
Chemical_Formula
  • C22H32O3
Legacy_Concept_Name
  • Medroxyprogesterone
CHEBI_ID
  • CHEBI:6715
FULL_SYN
  • MedroxyprogesteroneSYDTPNSC0027408
  • 6Alpha-methyl-4-pregnen-17alpha-ol-3,20-dioneSNNCI
  • medroxyprogesteronePTNCI-GLOSSCDR0000045265
  • CurretabSYDTPNSC0027408
  • (6Alpha)-17-hydroxy-6-methylpregn-4-ene-3,20-dioneSNNCI
  • MedroxyprogesteronePTNCI
  • CurretabBRNCI
  • 17Alpha-hydroxy-6alpha-methylprogesteroneSNNCI
  • 6Alpha-methyl-17alpha-hydroxyprogesteroneSNNCI
  • MEDROXYPROGESTERONEPTFDAHSU1C9YRES
DEFINITION
  • A synthetic derivative of progesterone administered as an acetate salt (medroxyprogesterone acetate) with antiestrogenic activity. As a do all progestins, medroxyprogesterone binds to and activates nuclear receptors which subsequently bind to and activate target genes for transcription. As an antiestrogen, this agent may inhibit the growth-stimulating effects of estrogen on estrogen-sensitive tumor cells. (NCI04)NCI
code
  • C629
sameAs
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