About: LMP-2:340-349 Peptide Vaccine     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • LMP-2:340-349 Peptide Vaccine
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • LMP-2:340-349 Peptide Vaccine
UMLS_CUI
  • C1831952
PDQ_Open_Trial_Search_ID
  • 504594
PDQ_Closed_Trial_Search_ID
  • 504594
Legacy_Concept_Name
  • LMP-2_340-349_Peptide_Vaccine
FULL_SYN
  • LMP-2:340-349 Peptide VaccinePTNCI
DEFINITION
  • A peptide vaccine containing amino acids residues from 340 through 349 of the latent membrane protein-2 (LMP-2) of the Epstein-Barr virus (EBV) with potential immunostimulating and antineoplastic activities. LMP-2, an EBV transmembrane protein, is expressed in various malignancies including nasopharyngeal cancer and EBV-positive Hodgkin's disease. Vaccination with the LMP-2:340-349 peptide may boost the immune system to mount a specific cytotoxic T-lymphocyte (CTL) response against LMP-2 producing cells, resulting in cell lysis and inhibition of cancer cell proliferation.NCI
code
  • C62767
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