About: Telomerase Peptide Vaccine GV1001     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Telomerase Peptide Vaccine GV1001
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Telomerase Peptide Vaccine GV1001
UMLS_CUI
  • C1831942
PDQ_Open_Trial_Search_ID
  • 502114
PDQ_Closed_Trial_Search_ID
  • 502114
Legacy_Concept_Name
  • GV1001
FULL_SYN
  • Telomerase Peptide Vaccine GV1001PTNCI
  • GV1001CNNCI
  • PrimoVaxFBNCI
DEFINITION
  • A synthetic peptide vaccine, containing 16 amino acid residues (611-626) of the human telomerase reverse transcriptase catalytic subunit (hTERT), with potential antineoplastic activity. Telomerase, a reverse transcriptase normally repressed in healthy cells, is overexpressed in most cancer cells and plays a key role in cellular proliferation. Vaccination with the telomerase peptide GV1001 may activate the immune system to mount a cytotoxic T-lymphocyte (CTL) response against telomerase-expressing cells.NCI
code
  • C62756
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