About: CHP-NY-ESO-1 Peptide Vaccine IMF-001

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: CHP-NY-ESO-1 Peptide Vaccine IMF-001 Goto Sponge NotDistinct Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	CHP-NY-ESO-1 Peptide Vaccine IMF-001
rdfs:subClassOf	Cancer Vaccines
Semantic_Type	Pharmacologic Substance Immunologic Factor
Preferred_Name	CHP-NY-ESO-1 Peptide Vaccine IMF-001
UMLS_CUI	C1831881
PDQ_Open_Trial_Search_ID	489132
PDQ_Closed_Trial_Search_ID	489132
Legacy_Concept_Name	CHP-NY-ESO-1_Peptide_Vaccine
FULL_SYN	Cholesteryl Pullulan-NY-ESO-1 Vaccine IMF-001SYNCI CHP-NY-ESO-1 Peptide Vaccine IMF-001PTNCI IMF-001CNNCI
DEFINITION	A peptide cancer vaccine containing nanoparticles of cholesteryl hydrophobized pullulan (CHP) complexed with the cancer-testis antigen NY-ESO-1 protein, with potential immunostimulating and antineoplastic activities. Upon administration, CHP-NY-ESO-1 peptide vaccine IMF-001 may stimulate the host immune system to mount a humoral and cytotoxic T-cell response against tumor cells expressing NY-ESO-1 antigen, resulting in tumor cell lysis. The self-aggregating CHP, composed of a pullulan backbone and cholesterol branches, forms stable colloidal nanoparticles in water. NY-ESO-1, an antigen found in normal testis, is upregulated in various cancers, including bladder, breast, hepatocellular, melanoma, and prostate cancers.NCI
code	C62598

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 18 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software