About: Hsp90 Inhibitor BIIB021

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Hsp90 Inhibitor BIIB021 Goto Sponge NotDistinct Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Hsp90 Inhibitor BIIB021
rdfs:subClassOf	Heat Shock Protein Inhibitor nodeID://b654464 nodeID://b654465 nodeID://b654466 nodeID://b654467
Has_Target	HSP90 Heat-Shock Proteins
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Pharmacologic Substance
Preferred_Name	Hsp90 Inhibitor BIIB021
UMLS_CUI	C1831929
CAS_Registry	848695-25-0
FDA_UNII_Code	851B9FQ7Q0
Contributing_Source	FDA
PDQ_Open_Trial_Search_ID	497050
PDQ_Closed_Trial_Search_ID	497050
Chemical_Formula	C14H15ClN6O
Legacy_Concept_Name	CNF2024
FULL_SYN	Hsp90 Inhibitor BIIB021PTNCI Hsp90 Antagonist CNF2024SYNCI BIIB021PTFDA851B9FQ7Q0 CNF2024CNNCI BIIB021CNNCI BIIB-021CNNCI
DEFINITION	An orally active inhibitor of heat shock protein 90 (HSP90) with potential antineoplastic activity. HSP90, a chaperon protein upregulated in a variety of tumor cells, regulates the folding and degradation of many oncogenic signaling proteins. HSP90 inhibitor CNF2024 specifically blocks active HSP90, thereby inhibiting its chaperon function and promoting the degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival. As a result, CNF2024 has the potential to inhibit the growth of a wide range of cancer cells in both solid tumors and blood-based cancers.NCI
code	C62517
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0542104

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 78 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2025 OpenLink Software