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AttributesValues
rdf:type
rdfs:label
  • Pilocarpine
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Pilocarpine
UMLS_CUI
  • C0031923
CAS_Registry
  • 92-13-7
FDA_UNII_Code
  • 01MI4Q9DI3
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used to increase salivation in people who have dry mouth caused by opioids or radiation therapy. Pilocarpine belongs to the family of drugs called alkaloids.NCI-GLOSS
Chemical_Formula
  • C11H16N2O2
Legacy_Concept_Name
  • Pilocarpine_Base
CHEBI_ID
  • CHEBI:8207
FULL_SYN
  • PilocarpinePTNCI
  • Ocusert PiloBRNCI
  • pilocarpinePTNCI-GLOSSCDR0000045573
  • PILOCARPINEPTFDA01MI4Q9DI3
DEFINITION
  • A natural alkaloid extracted from plants of the genus Pilocarpus with cholinergic agonist activity. As a cholinergic parasympathomimetic agent, pilocarpine predominantly binds to muscarinic receptors, thereby inducing exocrine gland secretion and stimulating smooth muscle in the bronchi, urinary tract, biliary tract, and intestinal tract. When applied topically to eyes, this agent stimulates the sphincter pupillae to contract, resulting in miosis; stimulates the ciliary muscle to contract, resulting in spasm of accommodation; and may cause a transitory rise in intraocular pressure followed by a more persistent fall due to opening of the trabecular meshwork and an increase in the outflow of aqueous humor.NCI
code
  • C62068
sameAs
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