About: Hydralazine     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Hydralazine
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Hydralazine
NSC_Code
  • 126699
UMLS_CUI
  • C0020223
CAS_Registry
  • 86-54-4
FDA_UNII_Code
  • 26NAK24LS8
Contributing_Source
  • FDA
Chemical_Formula
  • C8H8N4
Legacy_Concept_Name
  • Hydralazine_Base
CHEBI_ID
  • CHEBI:5775
FULL_SYN
  • HydralazineSYDTPNSC0126699
  • HydralazinePTNCI
  • 1(2H)-Phthalazinone HydrazoneSNNCI
  • 1(2H)-Phthalazinone HydrazonePTDCP02098
  • HYDRALAZINEPTFDA26NAK24LS8
DEFINITION
  • A phthalazine derivative with antihypertensive effects. Hydralazine exerts its vasodilatory effects through modification of the contractile state of arterial vascular smooth muscle by altering intracellular calcium release, and interfering with smooth muscle cell calcium influx. This agent also causes inhibition of phosphorylation of myosin protein or chelation of trace metals required for smooth muscle contraction, thereby resulting in an increase in heart rate, stroke volume and cardiac output.NCI
code
  • C62032
sameAs
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