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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Sulbactam
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Sulbactam
UMLS_CUI
  • C0038665
CAS_Registry
  • 68373-14-8
FDA_UNII_Code
  • S4TF6I2330
Contributing_Source
  • FDA
Chemical_Formula
  • C8H11NO5S
Legacy_Concept_Name
  • Sulbactam
CHEBI_ID
  • CHEBI:9321
FULL_SYN
  • (2S,5R)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid 4,4-dioxideSNNCI
  • SULBACTAMPTFDAS4TF6I2330
  • CP 45899CNNCI
  • SulbactamPTNCI
DEFINITION
  • A semi-synthetic beta-lactamase inhibitor. The beta-lactam ring of sulbactam irreversibly binds to beta-lactamase at or near its active site, thereby blocking enzyme activity and preventing metabolism of other beta-lactam antibiotics by the enzyme. Combining this agent with a beta-lactamase susceptible antibiotic, such as penicillins or a cephalosporin, to treat infections caused by beta-lactamase producing organisms, results in a decreased turnover rate of the beta-lactamase sensitive antibiotic and enhances its antibacterial activity.NCI
code
  • C61957
sameAs
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