About: Rosuvastatin Calcium     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Rosuvastatin Calcium
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Rosuvastatin Calcium
UMLS_CUI
  • C1101751
CAS_Registry
  • 147098-20-2
Accepted_Therapeutic_Use_For
  • Atherosclerosis
FDA_UNII_Code
  • 83MVU38M7Q
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used to lower the amount of cholesterol and other harmful substances, such as triglycerides, in the blood. It is also being studied in the prevention and treatment of some types of cancer and other conditions. Crestor blocks an enzyme that helps make cholesterol in the body and it helps break down cholesterol. It also may cause cancer cells to die and may inhibit the growth of blood vessels that cancer cells need to grow. It is a type of HMG-CoA reductase inhibitor and a type of statin.NCI-GLOSS
Chemical_Formula
  • 2C22H27FN3O6S.Ca
Legacy_Concept_Name
  • Rosuvastatin_Calcium
FULL_SYN
  • ROSUVASTATIN CALCIUMPTFDA83MVU38M7Q
  • rosuvastatin calciumPTNCI-GLOSSCDR0000663321
  • CrestorPTNCI-GLOSSCDR0000663322
  • CrestorBRNCI
  • CrestorPTDCP50551
  • Rosuvastatin CalciumPTNCI
DEFINITION
  • The calcium salt form of rosuvastatin, a statin with antilipidemic activity. Rosuvastatin selectively and competitively binds to and inhibits hepatic hydroxymethyl-glutaryl coenzyme A (HMG-CoA) reductase, the enzyme which catalyzes the conversion of HMG-CoA to mevalonate, a precursor of cholesterol. This leads to a decrease in hepatic cholesterol levels and increase in uptake of LDL cholesterol.NCI
code
  • C61933
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 58 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software