About: Rimantadine Hydrochloride     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Rimantadine Hydrochloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Rimantadine Hydrochloride
NSC_Code
  • 206764
UMLS_CUI
  • C0733408
CAS_Registry
  • 1501-84-4
FDA_UNII_Code
  • JEI07OOS8Y
Contributing_Source
  • FDA
Chemical_Formula
  • C12H21N.HCl
Legacy_Concept_Name
  • Rimantadine_Hydrochloride
FULL_SYN
  • Adamantane, 1-(1-aminoethyl)-, HydrochlorideSNNCI
  • Rimantadine HydrochloridePTNCI
  • JP 61CNNCI
  • RIMANTADINE HYDROCHLORIDEPTFDAJEI07OOS8Y
  • EXP 126CNNCI
  • 1-(1-Aminoethyl)adamantane HydrochlorideSNNCI
  • MeradaneBRNCI
  • alpha-Methyl-1-adamantanemethylamine HydrochlorideSNNCI
  • FlumadineBRNCI
DEFINITION
  • The hydrochloride salt form of rimantadine, a cyclic amine and alpha-methyl derivative of amantadine with antiviral activity. Although the exact mechanism of action of rimantadine is not understood, this agent appears to exert its antiviral effect against influenza A virus by interfering with the function of the transmembrane domain of the viral M2 protein, thereby preventing the uncoating of the virus and subsequent release of infectious viral nucleic acids into the cytoplasm of infected cells.NCI
code
  • C61928
sameAs
http://linked.open...y/mesh/hasConcept
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