About: Penbutolol Sulfate     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Penbutolol Sulfate
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Penbutolol Sulfate
UMLS_CUI
  • C0282292
CAS_Registry
  • 38363-32-5
FDA_UNII_Code
  • US71433228
Contributing_Source
  • FDA
Chemical_Formula
  • 2C18H29NO2.H2SO4
Legacy_Concept_Name
  • Penbutolol_Sulfate
CHEBI_ID
  • CHEBI:7955
FULL_SYN
  • Penbutolol SulfatePTNCI
  • LevatolBRNCI
  • PENBUTOLOL SULFATEPTFDAUS71433228
DEFINITION
  • The sulfate salt form of penbutolol, a lipophilic, nonselective beta-adrenergic receptor antagonist with anti-anginal and antihypertensive activities. Penbutolol competitively binds to and blocks beta-1 adrenergic receptors in the heart, thereby decreasing cardiac contractility and rate. This leads to a reduction in cardiac output and lowers blood pressure. In addition, bisoprolol prevents the release of renin, a hormone secreted by the kidneys that causes constriction of blood vessels.NCI
code
  • C61882
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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