About: Hydrocortisone Acetate     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Hydrocortisone Acetate
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Hydrocortisone Acetate
UMLS_CUI
  • C0063077
CAS_Registry
  • 50-03-3
FDA_UNII_Code
  • 3X7931PO74
Contributing_Source
  • FDA
Chemical_Formula
  • C23H32O6
Legacy_Concept_Name
  • Hydrocortisone_Acetate
CHEBI_ID
  • CHEBI:17609
FULL_SYN
  • Hydrocortisone AcetatePTNCI
  • HYDROCORTISONE ACETATEPTFDA3X7931PO74
DEFINITION
  • The synthetic acetate salt form of hydrocortisone, a corticosteroid with anti-inflammatory and immunosuppressive properties. Hydrocortisone acetate initially binds to the cytoplasmic glucocorticoid receptor; then the receptor-ligand complex is translocated to the nucleus where it initiates the transcription of genes encoding for anti-inflammatory mediators, such as cytokines and lipocortins. Lipocortins inhibit phospholipase A2, thereby blocking the release of arachidonic acid from membrane phospholipids and preventing the synthesis of prostaglandins and leukotrienes.NCI
code
  • C61785
sameAs
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