About: 4-Hydroxybutanoic Acid     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • 4-Hydroxybutanoic Acid
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • 4-Hydroxybutanoic Acid
UMLS_CUI
  • C0673093
CAS_Registry
  • 591-81-1
FDA_UNII_Code
  • 30IW36W5B2
Contributing_Source
  • FDA
Chemical_Formula
  • C4H8O3
Legacy_Concept_Name
  • Gamma-Hydroxybutyric_Acid
CHEBI_ID
  • CHEBI:30830
FULL_SYN
  • 4-Hydroxybutanoic AcidPTNCI
  • 4-HYDROXYBUTANOIC ACIDPTFDA30IW36W5B2
  • Gamma-Hydroxybutyric AcidSYNCI
  • AnetaminSYNCI
  • 4-Hydroxybutyric AcidSYNCI
  • gamma-HydroxybutyrateSYNCI
DEFINITION
  • A naturally occurring short-chain fatty acid, and immediate precursor of gamma amino butyric acid (GABA) with neuromodulatory and anesthetic properties. 4-Hydroxybutyric Acid (GHB) is found in all human tissues, with the highest concentration in the brain. This agent stimulates the GHB receptor, and to a lesser extent GABA-B receptors. Although, the precise function and metabolic pathways of GHB are not fully understood, this agent easily crosses the blood-brain barrier, and affects the activities and levels of dopamine, acetylcholine, dynorphin and serotonin. The primary effect of GHB is central nervous system depression, thereby, its main usage is to induce anesthesia.NCI
code
  • C61773
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