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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Ethambutol
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Ethambutol
UMLS_CUI
  • C0014964
CAS_Registry
  • 74-55-5
FDA_UNII_Code
  • 8G167061QZ
Contributing_Source
  • FDA
Chemical_Formula
  • C10H24N2O2
Legacy_Concept_Name
  • Ethambutol
CHEBI_ID
  • CHEBI:4877
FULL_SYN
  • ETHAMBUTOLPTFDA8G167061QZ
  • EthambutolPTNCI
DEFINITION
  • An antibiotic with bacteriostatic, antimicrobial and antitubercular properties. Ethambutol interferes with the biosynthesis of arabinogalactan, a major polysaccharide of the mycobacterial cell wall. It inhibits the polymerization of cell wall arabinan of arabinogalactan and lipoarabinomannan by blocking arabinosyl transferases and induces the accumulation of D-arabinofuranosyl-P-decaprenol, an intermediate in arabinan biosynthesis. This results in halting bacterial growth.NCI
code
  • C61755
sameAs
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