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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Eprosartan
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Eprosartan
UMLS_CUI
  • C0287041
CAS_Registry
  • 133040-01-4
FDA_UNII_Code
  • 2KH13Z0S0Y
Contributing_Source
  • FDA
Chemical_Formula
  • C23H24N2O4S
Legacy_Concept_Name
  • Eprosartan
CHEBI_ID
  • CHEBI:4814
FULL_SYN
  • EPROSARTANPTFDA2KH13Z0S0Y
  • EprosartanPTNCI
DEFINITION
  • A competitive and reversible angiotensin II receptor antagonist with anti-hypertensive property. Eprosartan blocks the binding of angiotensin II to the angiotensin (AT)1 receptor in vascular smooth muscle, thereby blocking the principal pressor action of angiotensin II on the renin-angiotensin system resulting in vascular dilatation. In addition, this agent blocks angiotensin II -induced stimulation of aldosterone synthesis and secretion by the adrenal cortex, cardiac contraction, renal resorption of sodium, activity of the sympathetic nervous system, and smooth muscle cell growth. Furthermore, eprosartan inhibits sympathetic norepinephrine production, thereby further reducing blood pressure.NCI
code
  • C61749
sameAs
http://linked.open...y/mesh/hasConcept
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