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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Edetate Disodium
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Edetate Disodium
UMLS_CUI
  • C0012695
CAS_Registry
  • 6381-92-6
FDA_UNII_Code
  • 7FLD91C86K
Contributing_Source
  • FDA
Chemical_Formula
  • C10H12N2O8.2"H".2Na.2H2O
Legacy_Concept_Name
  • Edetate_Disodium
CHEBI_ID
  • CHEBI:64758
FULL_SYN
  • EDETATE DISODIUMPTFDA7FLD91C86K
  • Edetate DisodiumPTNCI
DEFINITION
  • The disodium salt form of edetate, a heavy metal chelating agent with anti-hypercalcemic and anti-arrhythmic properties. Edetate, a heavy metal antagonist, chelates divalent and trivalent metals, forming soluble stable complexes which are readily excreted by the kidneys, thereby can be used to lower serum calcium concentrations. In addition, this agent exerts a negative inotropic effect on the heart through a transiently induced hypocalcemic state, thereby antagonizing the inotropic and chronotropic effects of digitalis glycosides on the ventricles of the heart. Upon ocular administration, edetate exerts its ophthalmic effect by chelating calcium to form soluble complexes, thereby removing corneal calcium deposits.NCI
code
  • C61741
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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