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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Deserpidine
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Deserpidine
UMLS_CUI
  • C0175158
CAS_Registry
  • 131-01-1
FDA_UNII_Code
  • 9016E3VB47
Contributing_Source
  • FDA
Chemical_Formula
  • C32H38N2O8
Legacy_Concept_Name
  • Deserpidine
CHEBI_ID
  • CHEBI:27478
FULL_SYN
  • DeserpidinePTNCI
  • HarmonylBRNCI
  • DESERPIDINEPTFDA9016E3VB47
DEFINITION
  • An ester alkaloid derived from Rauwolfia canescens with antihypertensive activity. Deserpidine is a competitive inhibitor of the angiotensin converting enzyme (ACE). By competing with angiotensin I for ACE, deserpidine blocks the conversion of angiotensin I to angiotensin II, which is a potent vasoconstrictor. Reduced level of serum angiotensin II causes a decrease in blood pressure. Deserpidine also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex.NCI
code
  • C61699
sameAs
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