About: Almotriptan Malate     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Almotriptan Malate
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Almotriptan Malate
UMLS_CUI
  • C0937898
CAS_Registry
  • 181183-52-8
FDA_UNII_Code
  • PJP312605E
Contributing_Source
  • FDA
Chemical_Formula
  • C17H25N3O2S.C4H6O5
Legacy_Concept_Name
  • Almotriptan_Malate
CHEBI_ID
  • CHEBI:53781
FULL_SYN
  • AxertBRNCI
  • Almotriptan MalatePTNCI
  • ALMOTRIPTAN MALATEPTFDAPJP312605E
DEFINITION
  • The malate salt of almotriptan, a sulfonamide triptan with vasoconstrictor activity. Almotriptan selectively binds to and activates serotonin 5-HT 1B and 1D receptors in the central nervous system (CNS), thereby causing cerebral blood vessel constriction. This may lead to pain relief from vascular headaches. Almotriptan may also relieve vascular headaches by preventing the release of vasoactive neuropeptides from perivascular trigeminal axons in the dura mater during a migraine, by reducing extravasation of plasma proteins, and by decreasing the release of other mediators of inflammation from the trigeminal nerve.NCI
code
  • C61628
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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