About: Melan-A VLP Vaccine     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Melan-A VLP Vaccine
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
  • Immunologic Factor
Preferred_Name
  • Melan-A VLP Vaccine
UMLS_CUI
  • C1831836
PDQ_Open_Trial_Search_ID
  • 506112
PDQ_Closed_Trial_Search_ID
  • 506112
Legacy_Concept_Name
  • Melan-A_VLP_Vaccine
FULL_SYN
  • CYT004-MelQbG10ABNCI
  • Melan-A VLP VaccinePTNCI
DEFINITION
  • A vaccine consisting of the melanocyte differentiation antigen Melan A (also called MART-1) encapsulated in noninfectious virus-like particles (VLP) with potential immunostimulating and antineoplastic activities. Upon administration, Melan-A VLP vaccine may activate the immune system to exert a specific cytotoxic T lymphocyte (CTL) response against cancer cells expressing the Melan A antigen, resulting in tumor cell lysis. Melan A is an antigen that is upregulated in most melanomas. VLP stimulates the immune system and promotes the CTL response.NCI
code
  • C61495
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