About: GI-4000 Vaccine     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • GI-4000 Vaccine
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • GI-4000 Vaccine
UMLS_CUI
  • C1831831
PDQ_Open_Trial_Search_ID
  • 486259
PDQ_Closed_Trial_Search_ID
  • 486259
Legacy_Concept_Name
  • GI-4000_Vaccine
FULL_SYN
  • GI-4000 VaccinePTNCI
DEFINITION
  • A vaccine containing a heat-killed recombinant Saccharomyces cerevisiae yeast transfected with mutated forms of Ras, an oncogene frequently found in solid tumors, with potential immunostimulant and antitumor activity. Upon administration, GI-4000 vaccine elicits an immune response by stimulating a specific cytotoxic T-cell response against the mutated forms of Ras. This may lead to a destruction of cancer cells expressing a Ras mutation.NCI
code
  • C61489
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