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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Ionomycin
rdfs:subClassOf
Semantic_Type
  • Antibiotic
Preferred_Name
  • Ionomycin
UMLS_CUI
  • C0022020
CAS_Registry
  • 56092-81-0
PDQ_Open_Trial_Search_ID
  • 43046
PDQ_Closed_Trial_Search_ID
  • 43046
Legacy_Concept_Name
  • Ionomycin
CHEBI_ID
  • CHEBI:63954
FULL_SYN
  • IonomycinPTNCI
  • ionomycinPTNCI-GLOSSCDR0000045998
DEFINITION
  • A polyether antibiotic isolated from Streptomyces conglobatus sp. nov. Trejo with antineoplastic activity. Ionomycin is a calcium ionophore that increases intracellular Ca++ levels, possibly relating to endonuclease activation of lymphocytes and decreased ratio of Bcl-2 to Bax and ultimately apoptosis. In addition, this agent is used to investigate the role of intracellular calcium in cellular processes. (NCI)NCI
code
  • C596
sameAs
http://linked.open...y/mesh/hasConcept
is someValuesFrom of
is sameAs of
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