About: Yttrium Y-90-DOTA-Girentuximab     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Yttrium Y-90-DOTA-Girentuximab
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Yttrium Y-90-DOTA-Girentuximab
UMLS_CUI
  • C1710703
PDQ_Open_Trial_Search_ID
  • 465788
PDQ_Closed_Trial_Search_ID
  • 465788
Legacy_Concept_Name
  • Yttrium_Y_90_DOTA_Chimeric_Monoclonal_Antibody_cG250
FULL_SYN
  • Yttrium-90 DOTA Conjugated Chimeric MoAb G250SYNCI
  • 90Y-DOTA-cG250ABNCI
  • Yttrium Y-90-DOTA-GirentuximabPTNCI
  • Yttrium Y 90-DOTA-Chimeric Monoclonal Antibody cG250SYNCI
DEFINITION
  • A radioimmunoconjugate comprised of the chimeric monoclonal antibody cG250 conjugated with the bifunctional, macrocyclic chelating agent tetra-azacyclododecanetetra-acetic acid (DOTA) and labeled with the beta-emitting radioisotope yttrium 90. The antibody moiety of yttrium 90 DOTA chimeric monoclonal antibody cG250 binds to renal cell carcinoma cells expressing the G250 antigen, thereby selectively delivering a cytotoxic dose of beta radiation.NCI
code
  • C53409
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