About: Iodine I-124 Girentuximab

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Attributes	Values
rdf:type	Class
rdfs:label	Iodine I-124 Girentuximab
rdfs:subClassOf	Radioimmunoconjugate
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Amino Acid, Peptide, or Protein Immunologic Factor
Preferred_Name	Iodine I-124 Girentuximab
NCI_META_CUI	CL383142
CAS_Registry	1011710-99-8
FDA_UNII_Code	P0I0FT82VK
Contributing_Source	FDA
PDQ_Open_Trial_Search_ID	465493
PDQ_Closed_Trial_Search_ID	465493
Legacy_Concept_Name	Iodine_I_124_Chimeric_Monoclonal_Antibody_cG250
FULL_SYN	Iodine I-124 GirentuximabPTNCI Iodine I 124 Chimeric Monoclonal Antibody G250SYNCI I 124 MoAb cG250ABNCI GIRENTUXIMAB I-124PTFDAP0I0FT82VK 124IcG250CNNCI RedectaneBRNCI 124I-cG250ABNCI
DEFINITION	A radioimmunoconjugate comprised of the chimeric monoclonal antibody G250 conjugated with the positron emitter iodine I 124. The antibody moiety of iodine I 124 chimeric monoclonal antibody G250 may bind to renal cell carcinoma (RCC) cells that express the RCC-associated antigen G250, allowing detection of tumor-localized iodine I 124 with positron emission tomography (PET). G250 is a cell surface tumor-associated antigen (TAA) that is found in the majority of renal cell carcinomas.NCI
code	C53407

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