About: MLLT6 wt Allele     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • MLLT6 wt Allele
equivalentClass
OMIM_Number
  • 600328
GenBank_Accession_Number
  • NM_005937
Semantic_Type
  • Gene or Genome
Preferred_Name
  • MLLT6 wt Allele
UMLS_CUI
  • C1705622
GO_Annotation
  • regulation of transcription, DNA-dependentGO:0006355TAS29-SEP-2003CGAP
EntrezGene_ID
  • 4302
Legacy_Concept_Name
  • MLLT6_wt_Allele
HGNC_ID
  • HGNC:7138
FULL_SYN
  • AF17SYNCI
  • MLLT6SYNCI
  • MLLT6 wt AllelePTNCI
  • Myeloid/Lymphoid or Mixed-Lineage Leukemia (Trithorax Homolog, Drosophila); Translocated to, 6 wt AlleleSYNCI
Gene_Encodes_Product
  • AF-17 Protein
DEFINITION
  • Human MLLT6 wild-type allele is located in the vicinity of 17q21 and is approximately 22 kb in length. This allele, which encodes protein AF-17, is involved in the modulation of transcription by RNA polymerase II. Acute nonlymphocytic leukemia is associated with the translocation t(11;17)(q23;q21) of the gene and the MLL gene.NCIAtlas of Genetics and Cytogenetics in Hematology and Oncology
code
  • C53080
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