About: SH2B2 wt Allele     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • SH2B2 wt Allele
equivalentClass
OMIM_Number
  • 605300
GenBank_Accession_Number
  • NM_020979
Semantic_Type
  • Gene or Genome
Preferred_Name
  • SH2B2 wt Allele
UMLS_CUI
  • C1706670
GO_Annotation
  • SH3/SH2 adaptor protein activityGO:0005070TAS29-SEP-2003CGAP
  • antimicrobial humoral response (sensu Invertebrata)GO:0006960NR29-SEP-2003CGAP
  • JAK pathway signal transduction adaptor activityGO:0008269TAS29-SEP-2003CGAP
  • signal transductionGO:0007165TAS29-SEP-2003CGAP
  • cytoplasmGO:0005737TAS29-SEP-2003CGAP
EntrezGene_ID
  • 10603
Legacy_Concept_Name
  • APS_wt_Allele
HGNC_ID
  • HGNC:17381
FULL_SYN
  • SH2B2 wt AllelePTNCI
  • Adaptor Protein with Pleckstrin Homology and SRC Homology 2 Domains wt AlleleSYNCI
  • SH2B Adaptor Protein 2 wt AlleleSYNCI
Gene_Encodes_Product
  • SH2 and PH Domain-Containing Adapter Protein APS
DEFINITION
  • Human SH2B2 wild-type allele is located in the vicinity of 7q22 and is approximately 34 kb in length. This allele, which encodes SH2B adaptor protein 2, plays a role in the modulation of both insulin and B-cell antigen-dependent signaling pathways.NCI
code
  • C52368
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