About: FASN wt Allele     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • FASN wt Allele
equivalentClass
OMIM_Number
  • 600212
GenBank_Accession_Number
  • NM_004104
Semantic_Type
  • Gene or Genome
Preferred_Name
  • FASN wt Allele
UMLS_CUI
  • C1704658
GO_Annotation
  • fatty acid metabolismGO:0006631TAS29-SEP-2003CGAP
EntrezGene_ID
  • 2194
Legacy_Concept_Name
  • FASN_wt_Allele
HGNC_ID
  • HGNC:3594
FULL_SYN
  • MGC17164SYNCI
  • FASN wt AllelePTNCI
  • FASSYNCI
  • OA-519SYNCI
  • Fatty Acid Synthase wt AlleleSYNCI
  • MGC14367SYNCI
Gene_Encodes_Product
  • Fatty Acid Synthase
DEFINITION
  • Human FASN wild-type allele is located within 17q25 and is approximately 20 kb in length. This allele, which encodes fatty acid synthase protein, is involved in the biosynthesis of long-chain fatty acids. The FASN gene is overexpressed in many epithelial cancers and is associated with poor prognosis.NCI
DesignNote
  • Inhibition of FASN gene expression in cancer cells negatively regulates growth and induces apoptosis.
code
  • C50951
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