About: MMP3 wt Allele

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	MMP3 wt Allele
equivalentClass	nodeID://b634971
OMIM_Number	185250
GenBank_Accession_Number	NM_002422
Semantic_Type	Gene or Genome
Preferred_Name	MMP3 wt Allele
UMLS_CUI	C1705599
GO_Annotation	proteolysis and peptidolysisGO:0006508TAS29-SEP-2003CGAP extracellular spaceGO:0005615TAS29-SEP-2003CGAP stromelysin 1 activityGO:0004248TAS29-SEP-2003CGAP
EntrezGene_ID	4314
Legacy_Concept_Name	MMP3_wt_Allele
HGNC_ID	HGNC:7173
FULL_SYN	MMP3 wt AllelePTNCI SL-1SYNCI STR1SYNCI STMYSYNCI STMY1SYNCI TRANSINSYNCI Matrix Metalloproteinase 3 (Stromelysin 1, Progelatinase) wt AlleleSYNCI
Gene_Encodes_Product	Matrix Metalloproteinase 3
DEFINITION	Human MMP3 wild-type allele is located in the vicinity of 11q22.3 and is approximately 8 kb in length. This allele, which encodes stromelysin-1 protein, plays a role in the regulation of matrix remodeling via the activation of matrix metalloproteinase precursors. It is also involved in the inhibition of breast tumor cell metastasis through the degradation of plasminogen and laminin. The MMP3 gene is associated with osteoarthritis, rheumatoid arthritis and neoplasm invasiveness.NCI
code	C49733

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