About: ADAM11 wt Allele     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • ADAM11 wt Allele
equivalentClass
OMIM_Number
  • 155120
Homologous_Gene
  • ADAM Family, Peptidase M12b Family
GenBank_Accession_Number
  • NM_002390
Semantic_Type
  • Gene or Genome
Preferred_Name
  • ADAM11 wt Allele
UMLS_CUI
  • C1705375
GO_Annotation
  • integrin bindingGO:0005178TAS29-SEP-2003CGAP
  • plasma membraneGO:0005886TAS29-SEP-2003CGAP
  • integrin-mediated signaling pathwayGO:0007229TAS29-SEP-2003CGAP
  • metallopeptidase activityGO:0008237TAS29-SEP-2003CGAP
EntrezGene_ID
  • 4185
Legacy_Concept_Name
  • ADAM11_wt_Allele
HGNC_ID
  • HGNC:189
FULL_SYN
  • A Disintegrin and Metalloproteinase Domain 11 wt AlleleSYNCI
  • MDCSYNCI
  • ADAM11 wt AllelePTNCI
Gene_Encodes_Product
  • ADAM11 Protein
DEFINITION
  • Human ADAM11 wild-type allele is located in the vicinity of 17q21.3 and is approximately 21 kb in length. This allele, which encodes ADAM11 protein, plays a role in integrin binding. Expression of the ADAM 11 gene is disrupted in cancers such as breast and ovarian cancer due to gene rearrangements.NCI
code
  • C49543
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