About: Recombinant Interferon Beta     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Recombinant Interferon Beta
rdfs:subClassOf
Is_Related_To_Endogenous_Product
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Recombinant Interferon Beta
NSC_Code
  • 373361
  • 658933
UMLS_CUI
  • C0015980
CAS_Registry
  • 77238-31-4
Accepted_Therapeutic_Use_For
  • multiple sclerosis
PDQ_Open_Trial_Search_ID
  • 40468
PDQ_Closed_Trial_Search_ID
  • 40468
Legacy_Concept_Name
  • Therapeutic_Interferon_Beta
FULL_SYN
  • Beta InterferonSYNCI
  • Interferon, BetaSYNCI
  • Interferon-BSYNCI
  • Interferon BetaSYNCI
  • Recombinant Interferon BetaPTNCI
  • FeronFBNCI
  • NaferonFBNCI
  • Interferon-betaPTDCP31315
  • Human Interferon BetaSYNCI
  • BetantroneFBNCI
DEFINITION
  • A recombinant protein which is chemically identical to or similar to endogenous interferon beta with antiviral and anti-tumor activities. Endogenous interferons beta are cytokines produced by nucleated cells (predominantly natural killer cells) upon exposure to live or inactivated virus, double-stranded RNA or bacterial products. These agents bind to specific cell-surface receptors, resulting in the transcription and translation of genes with an interferon-specific response element. The proteins so produced mediate many complex effects, including antiviral (the most important being inhibition of viral protein synthesis), antiproliferative and immune modulating effects. The recombinant therapeutic forms of interferon beta are interferon beta 1-a and interferon beta 1-b. (NCI05)NCI
code
  • C495
sameAs
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