About: gp100:280-288(288V) Peptide Vaccine     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • gp100:280-288(288V) Peptide Vaccine
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • gp100:280-288(288V) Peptide Vaccine
NSC_Code
  • 683473
UMLS_CUI
  • C1831910
PDQ_Open_Trial_Search_ID
  • 492712
PDQ_Closed_Trial_Search_ID
  • 492712
Legacy_Concept_Name
  • gp100_280-288_288V_Peptide
FULL_SYN
  • gp100:280-288(288V) Peptide VaccinePTNCI
DEFINITION
  • A peptide vaccine consisting of the amino acids 280 through 288 of the melanoma antigen glycoprotein 100 (gp100) with potential antineoplastic activity. gp100:280-288(288V) peptide has a valine substitution at amino acid position 288 to improve immunogenicity. Vaccination with gp100:280-288(288V) peptide may stimulate the host immune system to mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for the gp100 antigen, resulting in decreased tumor growth.NCI
code
  • C49042
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