About: gp100:614-622 Peptide     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • gp100:614-622 Peptide
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • gp100:614-622 Peptide
NSC_Code
  • 732518
UMLS_CUI
  • C1711419
Legacy_Concept_Name
  • gp100_614-622_Peptide
FULL_SYN
  • gp100:614-622 PeptidePTNCI
DEFINITION
  • A synthetic peptide consisting of amino acid residues 614 through 622 of the melanoma-melanocyte antigen glycoprotein 100 (gp100). Vaccination with gp100:614-622 peptide may stimulate a cytotoxic T-cell immune response against tumor cells that express this antigen, resulting in decreased tumor growth and cell lysis. gp100 antigen is a self-antigen expressed by melanocytes, pigmented retinal cells and most melanoma lesions and recognized via class I and II HLA-restricted mechanisms.NCI
code
  • C48631
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