About: pNGVL4a-Sig/E7(detox)/HSP70 DNA Vaccine     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • pNGVL4a-Sig/E7(detox)/HSP70 DNA Vaccine
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • pNGVL4a-Sig/E7(detox)/HSP70 DNA Vaccine
UMLS_CUI
  • C1711127
PDQ_Open_Trial_Search_ID
  • 440127
PDQ_Closed_Trial_Search_ID
  • 440127
Legacy_Concept_Name
  • pNGVL4a-Sig_E7_detox_HSP70_DNA_Vaccine
FULL_SYN
  • pNGVL4a-Sig/E7(detox)/HSP70 DNA VaccinePTNCI
DEFINITION
  • An antigen-specific DNA cancer vaccine consisting of the coding sequences of a signal peptide (pNGVL4a-Sig), a detox form of the human papillomavirus type 16 (HPV-16) antigen E7, and the heat shock protein 70 (HSP70). Upon administration, this vaccine may generate potent cytotoxic CD8(+) T-cell responses against E7-expressing tumor cells, resulting in tumor cell death.NCI
code
  • C48418
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