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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Deferasirox
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Deferasirox
UMLS_CUI
  • C1619629
CAS_Registry
  • 201530-41-8
FDA_UNII_Code
  • V8G4MOF2V9
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used to treat too much iron in the blood caused by blood transfusions. It is being studied in the treatment of myelodysplastic syndromes (a group of diseases in which the bone marrow does not make enough healthy blood cells) and other conditions. Deferasirox binds to extra iron in the blood. The drug and the iron are passed from the body in urine. It is a type of chelating agent.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 435986
PDQ_Closed_Trial_Search_ID
  • 435986
Chemical_Formula
  • C21H15N3O4
Legacy_Concept_Name
  • Deferasirox
CHEBI_ID
  • CHEBI:49005
FULL_SYN
  • DeferasiroxPTNCI
  • deferasiroxPTNCI-GLOSSCDR0000514444
  • DeferasiroxPTDCP50595
  • ExjadePTNCI-GLOSSCDR0000535471
  • ExjadeBRNCI
  • 4-(3,5-Bis-(hydroxy-phenyl)-1,2,4)triazol-1-yl)-benzoic AcidSNNCI
  • DEFERASIROXPTFDAV8G4MOF2V9
DEFINITION
  • A synthetic, orally bioavailable, achiral, tridentate triazole derived from salicylic acid with iron-chelating activity. Deferasirox chelates iron at a 2:1 (ligand:iron) ratio. Because of its oral availability and long plasma half-life, this agent may be superior to desferrioxamine (desferal, DFO), which is orally inactive and has a short plasma half-life.NCI
code
  • C48384
sameAs
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