About: Matrix-Assisted Laser Desorption Ionization Mass Spectrometry     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Matrix-Assisted Laser Desorption Ionization Mass Spectrometry
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Laboratory Procedure
Preferred_Name
  • Matrix-Assisted Laser Desorption Ionization Mass Spectrometry
UMLS_CUI
  • C0282597
Contributing_Source
  • CDISC
ALT_DEFINITION
  • A mass spectrometric technique that is used for the analysis of large biomolecules. Analyte molecules are embedded in an excess matrix of small organic molecules that show a high resonant absorption at the laser wavelength used. The matrix absorbs the laser energy, thus inducing a soft disintegration of the sample- matrix mixture into free (gas phase) matrix and analyte molecules and molecular ions. In general, only molecular ions of the analyte molecules are produced and almost no fragmentation occurs. This makes the method well suited for molecular weight determinations and mixture analysis. (CHI)CDISC
Legacy_Concept_Name
  • Matrix-Assisted_Laser_Desorption_Ionization_Mass_Spectrometry
FULL_SYN
  • Matrix Assisted Laser Desorption Ionization Mass SpectrometrySYNCI
  • Matrix-Assisted Laser Desorption Ionization Mass SpectrometryPTNCI
  • Matrix-Assisted Laser Desorption Ionization Mass SpectrometrySYCDISC
  • MALDISYNCI
  • MALDIPTCDISC
DEFINITION
  • A mass spectrometric technique that is used for the analysis of large biomolecules. Analyte molecules are embedded in an excess matrix of small organic molecules that show a high resonant absorption at the laser wavelength used. The matrix absorbs the laser energy, thus inducing a soft disintegration of the sample- matrix mixture into free (gas phase) matrix and analyte molecules and molecular ions. In general, only molecular ions of the analyte molecules are produced and almost no fragmentation occurs. This makes the method well suited for molecular weight determinations and mixture analysis. (CHI)NCI
code
  • C48040
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