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AttributesValues
rdf:type
rdfs:label
  • Ziprasidone Mesylate
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Ziprasidone Mesylate
UMLS_CUI
  • C1170754
CAS_Registry
  • 199191-69-0
FDA_UNII_Code
  • 3X6SAX83JZ
Contributing_Source
  • FDA
Chemical_Formula
  • C21H21ClN4OS.CH4O3S.3H2O
Legacy_Concept_Name
  • Ziprasidone_Mesylate
CHEBI_ID
  • CHEBI:53757
FULL_SYN
  • ZIPRASIDONE MESYLATEPTFDA3X6SAX83JZ
  • Ziprasidone MesylatePTNCI
  • Geodon, for InjectionBRNCI
DEFINITION
  • The mesylate salt form of ziprasidone, a benzothiazolylpiperazine derivative and an atypical antipsychotic agent with an antischizophrenic property. Ziprasidone mesylate functions as an antagonist at the dopamine D2 and serotonin 5-HT2A and 5-HT1D receptors, and as an agonist at the 5-HT1A receptor. Ziprasidone mesylate also inhibits the synaptic reuptake of serotonin and norepinephrine. The mechanism of action by which ziprasidone mesylate exerts its antischizophrenic effect is unknown but is potentially mediated through a combination of dopamine D2 and serotonin 5-HT2 antagonism. This agent also has antagonistic activity against histamine H1 and alpha-1-adrenergic receptors.NCI
code
  • C48032
sameAs
is Has_Salt_Form of
is sameAs of
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