About: Valproate Sodium     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Valproate Sodium
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Valproate Sodium
UMLS_CUI
  • C0037567
CAS_Registry
  • 1069-66-5
FDA_UNII_Code
  • 5VOM6GYJ0D
Contributing_Source
  • FDA
Chemical_Formula
  • C8H15O2.Na
Legacy_Concept_Name
  • Valproate_Sodium
CHEBI_ID
  • CHEBI:9925
FULL_SYN
  • 2-Propylpentanoic Acid Sodium SaltSNNCI
  • VALPROATE SODIUMPTFDA5VOM6GYJ0D
  • Valproate SodiumPTNCI
  • DepaconBRNCI
  • ErgenylFBNCI
DEFINITION
  • The sodium salt form of valproic acid with anti-epileptic activity. Valproate sodium is converted into its active form, valproate ion, in blood. Although the mechanism of action remains to be elucidated, valproate sodium increases concentrations of gamma-aminobutyric acid (GABA) in the brain, probably due to inhibition of the enzymes responsible for the catabolism of GABA. This potentiates the synaptic actions of GABA. Valproate sodium may also affect potassium channels, thereby creating a direct membrane-stabilizing effect.NCI
code
  • C48029
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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