About: Tetracycline Hydrochloride     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Tetracycline Hydrochloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Tetracycline Hydrochloride
UMLS_CUI
  • C0546879
CAS_Registry
  • 64-75-5
FDA_UNII_Code
  • P6R62377KV
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 42307
PDQ_Closed_Trial_Search_ID
  • 42307
Chemical_Formula
  • C22H24N2O8.HCl
Legacy_Concept_Name
  • Tetracycline_Hydrochloride
FULL_SYN
  • (4S,4aS,5aS,6S,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide MonohydrochlorideSNNCI
  • Tetracycline HydrochloridePTNCI
  • TETRACYCLINE HYDROCHLORIDEPTFDAP6R62377KV
  • AchromycinSYDTPNSC0108579
  • AchromycinBRNCI
DEFINITION
  • The hydrochloride salt of tetracycline, a broad-spectrum naphthacene antibiotic produced semisynthetically from chlortetracycline, an antibiotic isolated from the bacterium Streptomyces aureofaciens. In bacteria, tetracycline blocks binding of aminoacyl-tRNA to the mRNA-ribosome complex, thereby inhibiting protein synthesis and bacterial cell growth. Because naturally fluorescing tetracycline binds to newly formed bone at the bone/osteoid interface, tetracycline-labeling of bone and fluorescence microscopy may be used to perform bone histomorphometry.NCI
code
  • C48020
sameAs
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is Has_Salt_Form of
is sameAs of
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