About: Prilocaine Hydrochloride     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Prilocaine Hydrochloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Prilocaine Hydrochloride
UMLS_CUI
  • C2936920
CAS_Registry
  • 1786-81-8
FDA_UNII_Code
  • MJW015BAPH
Contributing_Source
  • FDA
Chemical_Formula
  • C13H20N2O.HCl
Legacy_Concept_Name
  • Prilocaine_Hydrochloride
CHEBI_ID
  • CHEBI:32053
FULL_SYN
  • Prilocaine HydrochloridePTNCI
  • L-67CNNCI
  • PRILOCAINE HYDROCHLORIDEPTFDAMJW015BAPH
  • 2-(Propylamino)-o-propionotoluidide HydrochlorideSNNCI
  • CitanestBRNCI
  • XylonestBRNCI
DEFINITION
  • The hydrochloride salt form of prilocaine, an intermediate-acting local anesthetic of the amide type chemically related to lidocaine. Prilocaine hydrochloride binds to voltage-gated sodium ion channels in the neuronal membrane, thereby preventing the permeability of sodium ions. This leads to a stabilization of the neuronal membrane and inhibits depolarization and results in a reversible blockage of nerve impulse generation and propagation along nerve fibres and subsequent reversible loss of sensation.NCI
code
  • C48012
sameAs
is Has_Salt_Form of
is sameAs of
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