About: Azathioprine Sodium     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Azathioprine Sodium
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Azathioprine Sodium
NSC_Code
  • 39084
UMLS_CUI
  • C0887732
CAS_Registry
  • 55774-33-9
FDA_UNII_Code
  • AM94R510MS
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used to keep a patient from rejecting a transplanted kidney. It is also used in the treatment of rheumatoid arthritis that does not get better with other types of treatment. Azathioprine sodium blocks the growth of white blood cells and the synthesis of DNA, RNA, and protein. It is a type of immunosuppressant.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 39157
PDQ_Closed_Trial_Search_ID
  • 39157
Chemical_Formula
  • C9H6N7O2S.Na
Legacy_Concept_Name
  • Azathioprine_Sodium
FULL_SYN
  • ImuranSYDTPNSC0039084
  • ImurelSYDTPNSC0039084
  • azathioprine sodiumPTNCI-GLOSSCDR0000648945
  • ImurelFBNCI
  • ImuranBRNCI
  • Azathioprine SodiumPTNCI
  • AZATHIOPRINE SODIUMPTFDAAM94R510MS
DEFINITION
  • The sodium salt form of azathioprine, a pro-drug of purine analogue with immunosuppressive activity. Azathioprine is converted in vivo to its active metabolite 6-mercaptopurine (6-MP), which substitutes for the normal nucleoside and mistakenly gets incorporated into DNA sequences. This leads to inhibition of DNA, RNA, and protein synthesis. As a result, cell proliferation may be inhibited, particularly in lymphocytes and leukocytes.NCI
code
  • C47961
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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